CCNH antibody (clone 1B8), anti-human
€435.00
In stock
SKU
AC-AT1422a
Catalog Number: AC-AT1422a
Size: 100 µg
Isotype: mouse IgG2a kappa
Applications: WB, IHC, IF, E
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Size: 100 µg
Isotype: mouse IgG2a kappa
Applications: WB, IHC, IF, E
Request Information AC-AT1422a">Request Information
Background:
The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with CDK7 kinase and ring finger protein MAT1. The kinase complex is able to phosphorylate CDK2 and CDC2 kinases, thus functions as a CDK-activating kinase (CAK). This cyclin and its kinase partner are components of TFIIH, as well as RNA polymerase II protein complexes. They participate in two different transcriptional regulation processes, suggesting an important link between basal transcription control and the cell cycle machinery.
Other Names:
Cyclin-H, MO15-associated protein, p34, p37, CCNH
Antigen Type:
Recombinant Protein
Gene Name: CCNH
Gene ID: 902
NCBI Accession: NP_001230.1
Primary Accession: P51946
Other Accession: BC005280
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with CDK7 kinase and ring finger protein MAT1. The kinase complex is able to phosphorylate CDK2 and CDC2 kinases, thus functions as a CDK-activating kinase (CAK). This cyclin and its kinase partner are components of TFIIH, as well as RNA polymerase II protein complexes. They participate in two different transcriptional regulation processes, suggesting an important link between basal transcription control and the cell cycle machinery.
Other Names:
Cyclin-H, MO15-associated protein, p34, p37, CCNH
Antigen Type:
Recombinant Protein
Gene Name: CCNH
Gene ID: 902
NCBI Accession: NP_001230.1
Primary Accession: P51946
Other Accession: BC005280
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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