CCNH middle region polyclonal, anti-human, mouse, rat, rabbit, pig, horse, bovine, guinea pig

Background:
Regulates CDK7, the catalytic subunit of the CDK- activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II. Its expression and activity are constant throughout the cell cycle.

Other Names:
Cyclin-H, MO15-associated protein, p34, p37, CCNH

Immunogen:
The immunogen for anti-CCNH antibody: synthetic peptide directed towards the middle region of human CCNH

Gene Name:
CCNH
Gene Name:
902
NCBI Accession:
NP_001230
Primary Accession: P51946
Other Accession: NM_001239;NP_001230
Purification: Affinity Purified
Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.