CCNT1 Antibody (Center) Blocking peptide
€363.00
In stock
SKU
AC-BP10669c
Background:
CCNT1 belongs to the highlyconserved cyclin family, whose members are characterized by adramatic periodicity in protein abundance through the cell cycle.Cyclins function as regulators of CDK kinases. Different cyclinsexhibit distinct expression and degradation patterns whichcontribute to the temporal coordination of each mitotic event. Thiscyclin tightly associates with CDK9 kinase, and was found to be amajor subunit of the transcription elongation factor p-TEFb. Thekinase complex containing this cyclin and the elongation factor caninteract with, and act as a cofactor of human immunodeficiencyvirus type 1 (HIV-1) Tat protein, and was shown to be bothnecessary and sufficient for full activation of viraltranscription. This cyclin and its kinase partner were also foundto be involved in the phosphorylation and regulation of thecarboxy-terminal domain (CTD) of the largest RNA polymerase IIsubunit.
Other Names:
Cyclin-T1, CycT1, Cyclin-T, CCNT1
Gene Name: CCNT1
Gene ID: 904
Primary Accession: O60563
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
CCNT1 belongs to the highlyconserved cyclin family, whose members are characterized by adramatic periodicity in protein abundance through the cell cycle.Cyclins function as regulators of CDK kinases. Different cyclinsexhibit distinct expression and degradation patterns whichcontribute to the temporal coordination of each mitotic event. Thiscyclin tightly associates with CDK9 kinase, and was found to be amajor subunit of the transcription elongation factor p-TEFb. Thekinase complex containing this cyclin and the elongation factor caninteract with, and act as a cofactor of human immunodeficiencyvirus type 1 (HIV-1) Tat protein, and was shown to be bothnecessary and sufficient for full activation of viraltranscription. This cyclin and its kinase partner were also foundto be involved in the phosphorylation and regulation of thecarboxy-terminal domain (CTD) of the largest RNA polymerase IIsubunit.
Other Names:
Cyclin-T1, CycT1, Cyclin-T, CCNT1
Gene Name: CCNT1
Gene ID: 904
Primary Accession: O60563
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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