CCNT1 N-terminal region polyclonal, anti-human, mouse, rat, rabbit, pig, horse, bovine, N. gonorrhoeae, guinea pig, dog

Background:
Regulatory subunit of the cyclin-dependent kinase pair (CDK9/cyclin-T1) complex, also called positive transcription elongation factor B (P-TEFb), which is proposed to facilitate the transition from abortive to productive elongation by phosphorylating the CTD (carboxy-terminal domain) of the large subunit of RNA polymerase II (RNA Pol II). In case of HIV or SIV infections, binds to the transactivation domain of the viral nuclear transcriptional activator, Tat, thereby increasing Tat's affinity for the transactivating response RNA element (TAR RNA). Serves as an essential cofactor for Tat, by promoting RNA Pol II activation, allowing transcription of viral genes.

Other Names:
Cyclin-T1, CycT1, Cyclin-T, CCNT1

Immunogen:
The immunogen for anti-CCNT1 antibody: synthetic peptide directed towards the N terminal of human CCNT1

Gene Name:
CCNT1
Gene Name:
904
NCBI Accession:
NP_001231
Primary Accession: O60563
Other Accession: NM_001240;NP_001231
Purification: Affinity Purified
Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.