CCR10 Polyclonal Antibody
€0.00
In stock
SKU
ELK-ES11457
Catalog Number: ELK-ES11457
Reactivity: Human, Mouse
Applications: WB, ELISA
Information
Request Manual ELK-
Questions? Contact us!
Reactivity: Human, Mouse
Applications: WB, ELISA
Information
Request Manual ELK-
Questions? Contact us!
Background:
C-C motif chemokine receptor 10(CCR10) Homo sapiens Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC, based on the arrangement of the first 2 of the 4 conserved cysteine residues; the 2 cysteines are separated by a single amino acid in CXC chemokines and are adjacent in CC chemokines. CCR10 is the receptor for CCL27 (SCYA27; MIM 604833); CCR10-CCL27 interactions are involved in T cell-mediated skin inflammation (Homey et al., 2002 [PubMed 11821900])
Immunogen: Synthesized peptide derived from human protein . at AA range: 120-200
Isotype: Rabbit
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/ml
Observed band: 39
GeneID: CCR10 GPR2
Storage: -20°C/1 year
NOTE: For Research Use Only
C-C motif chemokine receptor 10(CCR10) Homo sapiens Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC, based on the arrangement of the first 2 of the 4 conserved cysteine residues; the 2 cysteines are separated by a single amino acid in CXC chemokines and are adjacent in CC chemokines. CCR10 is the receptor for CCL27 (SCYA27; MIM 604833); CCR10-CCL27 interactions are involved in T cell-mediated skin inflammation (Homey et al., 2002 [PubMed 11821900])
Immunogen: Synthesized peptide derived from human protein . at AA range: 120-200
Isotype: Rabbit
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/ml
Observed band: 39
GeneID: CCR10 GPR2
Storage: -20°C/1 year
NOTE: For Research Use Only
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