CCR2 polyclonal, anti-human, mouse, rat antibody

Background:
Chemokines play important roles in inflammation and critical for the recruitment of effector immune cells to sites of infection. Chemokines activate leukocytes by binding to G protein coupled receptors. The ever-growing chemokine receptor subtypes can be divided into 2 major groups, CXCR and CCR, based on the 2 major classes of chemokines. One of the CCR receptors, CCR1, is expressed on neutrophils, monocytes, lymphocytes, and eosinophils and binds the leukocyte chemoattractant and hemopoiesis regulator macrophage-inflammatory protein (MIP-1 ), eotaxin, as well as several other related chemokines. Mice lacking the chemokine receptor CCR1 have defects in neutrophil trafficking and proliferation.

Other Names:
CCR2A, CCR2B, Chemokine CC Motif Receptor 2, CKR2, Monocyte Chemotactic Protein 1 Receptor,

Primary Accession: O55193

Other Accession: NP_068638.1

Gene Name: Ccr2

Gene ID: 60463

Concentration (mg/ml): 0.5 mg/ml