CCR3 polyclonal, anti-human antibody

Background:
Chemokines play important roles in inflammation and critical for the recruitment of effector immune cells to sites of infection. Chemokines activate leukocytes by binding to G protein coupled receptors. The ever-growing chemokine receptor subtypes can be divided into 2 major groups, CXCR and CCR, based on the 2 major classes of chemokines. One of the CCR receptors, CCR3 (eotaxin receptor), is expressed on eosinophils and certain T cell population respond to a variety of CC chemokines apart from eotaxin, including RANTES, monocyte chemotactic protein (MCP)-2, MCP-3, and MCP-4. CCR3 facilitated infection by a more restricted subset of primary viruses, and binding of the CCR3 ligand, eotaxin, and inhibited infection by these isolates.

Other Names:
CMKBR3 , CKR3 , CD193 , CC-CKR-3 , C CKR-3 , CC-CKR-3 , CCR-3 , CCR3

Primary Accession: O54814

Other Accession: NP_446410

Gene Name: Ccr3

Gene ID: 117027

Concentration (mg/ml): 0.5 mg/ml