CCR7 Polyclonal Antibody

Background:
The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor.

Research Area: Cancer, Immunology, Signal Transduction

Synonyms:
BLR 2, BLR2, C C chemokine receptor type 7, C C CKR 7, C-C chemokine receptor type 7, C-C CKR-7, CC chemokine receptor 7, CC chemokine receptor type 7, CC CKR 7, CC-CKR-7, CCCKR7, CCR 7, CCR-7, Ccr7, CCR7, CD 197, CD197, CD197 antigen, CDw197, Chemokine (C C motif) receptor 7, Chemokine (C C) receptor 7, Chemokine C C motif receptor 7, Chemokine C C receptor 7, Chemokine receptor 7, Chemokine receptor 7-like protein, CMKBR7, EBI 1, EBI1, Ebi1h, EBV Induced G Protein Coupled Receptor 1, EBV-induced G-protein coupled receptor 1, Epstein Barr virus induced G protein coupled receptor, Epstein Barr virus induced gene 1, Epstein-Barr virus-induced G-protein coupled receptor 1, EVI 1, EVI1, Lymphocyte Specific G Protein Coupled Peptide Receptor, MGC108519, MIP 3 beta receptor, MIP-3 beta receptor, MIP3 Beta Receptor

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse CCR7

Swissprot: P32248,P47774

Calculated MW: 43 kDa
Observed MW: 48 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4

Concentration: 0.9 mg/mL
Dilution: WB 1:500-1:2000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Citation(s):
https://pubmed.ncbi.nlm.nih.gov/32030319/