CCR8 polyclonal (C-term), anti-human
€0.00
In stock
SKU
AC-AP10485b
Catalog Number: AC-AP10485b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB28557
Applications: WB, FC
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB28557
Applications: WB, FC
Datasheet
Request Information
Background:
CCR8 encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites. This receptor protein preferentially expresses in the thymus. I-309, thymus activation-regulated cytokine (TARC) and macrophage inflammatory protein-1 beta (MIP-1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues. CCR8 is located at the chemokine receptor gene cluster region.
Other Names:
C-C chemokine receptor type 8, C-C CKR-8, CC-CKR-8, CCR-8, CC chemokine receptor CHEMR1, CMKBRL2, Chemokine receptor-like 1, CKR-L1, GPR-CY6, GPRCY6, TER1, CDw198, CCR8, CKRL1, CMKBR8, CMKBRL2
Target/Specificity:
This CCR8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 305-335 amino acids of human CCR8.
Antigen Region:
305-335
Antigen Type: Synthetic Peptide
Gene Name: CCR8
Gene ID: 1237
Primary Accession: P51685
NCBI Accession: NP_005192.1
Other Accession: NP_005192.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
CCR8 encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites. This receptor protein preferentially expresses in the thymus. I-309, thymus activation-regulated cytokine (TARC) and macrophage inflammatory protein-1 beta (MIP-1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues. CCR8 is located at the chemokine receptor gene cluster region.
Other Names:
C-C chemokine receptor type 8, C-C CKR-8, CC-CKR-8, CCR-8, CC chemokine receptor CHEMR1, CMKBRL2, Chemokine receptor-like 1, CKR-L1, GPR-CY6, GPRCY6, TER1, CDw198, CCR8, CKRL1, CMKBR8, CMKBRL2
Target/Specificity:
This CCR8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 305-335 amino acids of human CCR8.
Antigen Region:
305-335
Antigen Type: Synthetic Peptide
Gene Name: CCR8
Gene ID: 1237
Primary Accession: P51685
NCBI Accession: NP_005192.1
Other Accession: NP_005192.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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