CCT4 polyclonal, anti-human, mouse, rat

Background:
The chaperonin containing TCP1 (MIM 186980) complex (CCT), also called the TCP1 ring complex, consists of 2 back-to-back rings, each containing 8 unique but homologous subunits, such as CCT4. CCT assists the folding of newly translated polypeptide substrates through multiple rounds of ATP-driven release and rebinding of partially folded intermediate forms. Substrates of CCT include the cytoskeletal proteins actin (see MIM 102560) and tubulin (see MIM 191130), as well as alpha-transducin (MIM 139330) (Won et al., 1998 [PubMed 9819444]).

Synonyms: CCT-DELTA, Cctd, SRB

Cellular Location: Cytoplasm Melanosome centrosome cilium basal body cytoskeleton microtubule organizing center

Immunogen:
Recombinant protein of human CCT4

Gene Symbol: CCT4

Gene ID: 10575

Swiss prot: P50991

Calculated MW: 58kDa

Recommended dilution:
WB 1:500-2000, IHC 1:50-200, IF 1:50-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.