CCT4 polyclonal (N-term), anti-human
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In stock
SKU
AC-AP14904a
Catalog Number: AC-AP14904a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB35233
Applications: IHC-P, WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB35233
Applications: IHC-P, WB
Datasheet
Request Information
Background:
The chaperonin containing TCP1 (MIM 186980) complex (CCT), also called the TCP1 ring complex, consists of 2 back-to-back rings, each containing 8 unique but homologous subunits, such as CCT4. CCT assists the folding of newly translated polypeptide substrates through multiple rounds of ATP-driven release and rebinding of partially folded intermediate forms. Substrates of CCT include the cytoskeletal proteins actin (see MIM 102560) and tubulin (see MIM 191130), as well as alpha-transducin (MIM 139330) (Won et al., 1998 [PubMed 9819444]).
Other Names:
T-complex protein 1 subunit delta, TCP-1-delta, CCT-delta, Stimulator of TAR RNA-binding, CCT4, CCTD, SRB
Target/Specificity:
This CCT4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 4-32 amino acids from the N-terminal region of human CCT4.
Antigen Region:
4-32
Antigen Type: Synthetic Peptide
Gene Name: CCT4
Gene ID: 10575
Primary Accession: P50991
NCBI Accession: NP_001243650.1;NP_006421.2
Other Accession: Q7TPB1; NP_006421.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
The chaperonin containing TCP1 (MIM 186980) complex (CCT), also called the TCP1 ring complex, consists of 2 back-to-back rings, each containing 8 unique but homologous subunits, such as CCT4. CCT assists the folding of newly translated polypeptide substrates through multiple rounds of ATP-driven release and rebinding of partially folded intermediate forms. Substrates of CCT include the cytoskeletal proteins actin (see MIM 102560) and tubulin (see MIM 191130), as well as alpha-transducin (MIM 139330) (Won et al., 1998 [PubMed 9819444]).
Other Names:
T-complex protein 1 subunit delta, TCP-1-delta, CCT-delta, Stimulator of TAR RNA-binding, CCT4, CCTD, SRB
Target/Specificity:
This CCT4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 4-32 amino acids from the N-terminal region of human CCT4.
Antigen Region:
4-32
Antigen Type: Synthetic Peptide
Gene Name: CCT4
Gene ID: 10575
Primary Accession: P50991
NCBI Accession: NP_001243650.1;NP_006421.2
Other Accession: Q7TPB1; NP_006421.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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