CCT5 polyclonal, anti-human, mouse, rat

Background:
The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Mutations in this gene cause hereditary sensory and autonomic neuropathy with spastic paraplegia (HSNSP). Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 5 and 13.

Synonyms: CCT-epsilon, CCTE, HEL-S-69, PNAS-102, TCP-1-epsilon

Cellular Location: Cytoplasm centrosome cytoskeleton microtubule organizing center

Immunogen:
Recombinant protein of human CCT5

Gene Symbol: CCT5

Gene ID: 22948

Swiss prot: P48643

Calculated MW: 60kDa

Recommended dilution:
WB 1:500-2000

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.