CD10 (clone HI10a) FITC, anti-human
€435.00
In stock
SKU
250999
Protein Family: Cellular Antigens, Peptidases
Pathway and Disease: Immune System
Description:
The CD10 (HI10a) antibody recognizes neutral endopeptidase, a 100-kDa type-II transmembrane glycoprotein, which is referred as the Common Acute Lymphoblastic Leukemia Antigen (CALLA). CD10 antigen is expressed on a wide variety of normal and neoplastic cells including some subset of B and T lymphoid progenitors, germinal center cells, some granulocytes and fibroblasts. CD10 is a marker of common (pre-B) acute lymphocytic leukemias in which CD19, HLA-II and CD9 antigens are coexpressed. CD10 is a regulator of B cell growth and proliferation by hydrolysis of peptides having either proliferative or anti-proliferative functions.
Alternate Names: Neprilysin, Neutral endopeptidase, NEP, Enkephalinase, Neutral endopeptidase 24.11, Atriopeptidase, Common acute lymphocytic leukemia antigen, CALLA, CD10 antigen, MME, EPN
Application Notes: FC with whole blood: 100 μl blood + 20 μl antibody; FC with cells: 10E6 cells + 20 μl antibody. FC: 1:200-1:1,000
Accession No.: P08473, NP_009218
Format: Each vial contains 2 ml IgG (100 tests) in PBS pH7.4, 0.1% BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at 4°C. Product is guaranteed 6 months from the date of shipment.
Product Citations:
Schlossman S. et al., eds. 1995. Leucocyte Typing V: White Cell Differentiation Antigens. P246, Oxford University Press, New York
Pathway and Disease: Immune System
Description:
The CD10 (HI10a) antibody recognizes neutral endopeptidase, a 100-kDa type-II transmembrane glycoprotein, which is referred as the Common Acute Lymphoblastic Leukemia Antigen (CALLA). CD10 antigen is expressed on a wide variety of normal and neoplastic cells including some subset of B and T lymphoid progenitors, germinal center cells, some granulocytes and fibroblasts. CD10 is a marker of common (pre-B) acute lymphocytic leukemias in which CD19, HLA-II and CD9 antigens are coexpressed. CD10 is a regulator of B cell growth and proliferation by hydrolysis of peptides having either proliferative or anti-proliferative functions.
Alternate Names: Neprilysin, Neutral endopeptidase, NEP, Enkephalinase, Neutral endopeptidase 24.11, Atriopeptidase, Common acute lymphocytic leukemia antigen, CALLA, CD10 antigen, MME, EPN
Application Notes: FC with whole blood: 100 μl blood + 20 μl antibody; FC with cells: 10E6 cells + 20 μl antibody. FC: 1:200-1:1,000
Accession No.: P08473, NP_009218
Format: Each vial contains 2 ml IgG (100 tests) in PBS pH7.4, 0.1% BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at 4°C. Product is guaranteed 6 months from the date of shipment.
Product Citations:
Schlossman S. et al., eds. 1995. Leucocyte Typing V: White Cell Differentiation Antigens. P246, Oxford University Press, New York
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