CD10 polyclonal, anti-human, mouse, rat

Background:
CD10, also called the common acute lymphoblastic leukemia antigen (CALLA) and neutral endopeptidase (NEP), is a type II integral membrane glycoprotein. CD10 acts as a zinc metalloprotease that cleaves a variety of biologically active peptides including Angiotensins I and II. It is expressed on early B and T lymphoid precursors, B blasts, some granulocytes, bone marrow stromal cells and certain epithelial cells including some tumor cell lines. CD10 is used as a marker of common acute lymphocytic leukemias and some lymphomas.

Alternative Name:
CALLA, NEP, Neutral endopeptidase, SFE, MME, Atriopeptidase, CALLA, CD10, CD10 antigen, Common acute lymphocytic leukemia antigen, DKFZp686O16152, EC 3.4.24.11, Enkephalinase, EPN, Membrane metallo endopeptidase (neutral endopeptidase, enkephalinase), Membrane metallo endopeptidase (neutral endopeptidase, enkephalinase, CALLA, CD10), Membrane metallo endopeptidase, Membrane metallo endopeptidase variant 1, Membrane metallo endopeptidase variant 2, Membrane metalloendopeptidase, Membrane metalloendopeptidase neutral endopeptidase enkephalinase, Membrane metalloendopeptidase neutral endopeptidase enkephalinase CALLA CD10, Membrane metalloendopeptidase variant 1, Membrane metalloendopeptidase variant 2, MGC126681, MGC126707, MME, NEP, NEP, Neprilysin, neprilysin-390, neprilysin-411, Neutral endopeptidase 24.11, Neutral endopeptidase, Neutral endopeptidase, membrane-associated, SFE, Skin fibroblast elastase,

Application Dilution:
WB:1:500-1:1,000
ICC:1:50-1:200
FC:1:50-1:100
IHC:1:50-1:200

Specificity: CD10 polyclonal antibody detects endogenous levels of CD10 protein.

Immunogen:
recombinant protein

MW: 100 kDa

Swiss-Prot: P08473(Human) Q61391(Mouse) P07861(Rat)

Purification & Purity:
ProA affinity purified

Format:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Storage:
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

For research use only, not for use in diagnostic procedure.