CD105 polyclonal, anti-human

Quantity: 100 µg

Background:
Endoglin (Osler-Rendu-Weber syndrome 1), CD105, is a type I membrane glycoprotein located on cell surfaces and is a part of the TGF beta receptor complex. Its gene is mapped to human chromosome 8. The protein consists of a homodimer of 180 kDA with disulfide links. It has been found on endothelial cells, activated macrophages, fibroblasts and smooth muscle cells. Endoglin has a role in the development of the cardiovascular system and in vascular remodeling and has been found to be elevated in pregnant women who subsequently develop preeclampsia.

Description:
Rabbit IgG polyclonal antibody for Endoglin (ENG) detection. Tested with WB in Human.

Synonyms:
AI528660 antibody, AI662476 antibody, CD 105 antibody, CD105 antibody, CD105 antigen antibody, EGLN_HUMAN antibody, END antibody, Endoglin antibody, ENG antibody, FLJ41744 antibody, HHT1 antibody, ORW antibody, ORW1 antibody, Osler Rendu Weber syndrome 1 antibody, RP11 228B15.2 antibody, S-endoglin antibody, SN6 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
E.coli-derived human CD105 recombinant protein (Position: E26-I384). Human CD105 shares 67% amino acid (aa) sequence identity with mouse CD105.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.