CD105 polyclonal, anti-human, mouse, rat, rabbit, pig, bovine, chicken
€422.00
In stock
SKU
251222
Catalog Nr.: 251222
Size: 0.1 mg
Isotype: Rabbit Ig
Applications: E, WB, IHC
Datasheet
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Size: 0.1 mg
Isotype: Rabbit Ig
Applications: E, WB, IHC
Datasheet
Request Information
Protein Family: Cell Adhesion Molecules, Cellular Antigens
Pathway and Disease: Signaling Molecules and Interaction
Description:
The CD105 antigen (endoglin) is a major glycoprotein of the vascular endothelium with a role in integrins and RGD receptors for endothelial cell adhesion. CD105 forms heteromeric complex with signaling receptors for transforming growth factor-beta. CD105 expression is restricted to endothelial cells in all tissues except bone marrow. Defects in CD105 are the cause of hereditary hemorrhagic telangiectasia type 1 (HHT1).
Alternate Names: CD105, Endoglin, ENG, END
Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500
Accession No.: P17813
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human CD105.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Product Citations:
Coomber B et al. 2013. University of Guelph. Thesis. Modulation of endothelial signaling molecule expression by TGF-B
Pathway and Disease: Signaling Molecules and Interaction
Description:
The CD105 antigen (endoglin) is a major glycoprotein of the vascular endothelium with a role in integrins and RGD receptors for endothelial cell adhesion. CD105 forms heteromeric complex with signaling receptors for transforming growth factor-beta. CD105 expression is restricted to endothelial cells in all tissues except bone marrow. Defects in CD105 are the cause of hereditary hemorrhagic telangiectasia type 1 (HHT1).
Alternate Names: CD105, Endoglin, ENG, END
Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500
Accession No.: P17813
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human CD105.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Product Citations:
Coomber B et al. 2013. University of Guelph. Thesis. Modulation of endothelial signaling molecule expression by TGF-B
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