CD105 polyclonal Cy3, anti-human, mosue, rat
€642.00
In stock
SKU
254549
Protein Family: Cell Adhesion Molecules, Cellular Antigens
Pathway and Disease: Signaling Molecules and Interaction
Description:
The CD105 antigen (endoglin) is a major glycoprotein of the vascular endothelium with a role in integrins and RGD receptors for endothelial cell adhesion. CD105 forms heteromeric complex with signaling receptors for transforming growth factor-beta. CD105 expression is restricted to endothelial cells in all tissues except bone marrow. Defects in CD105 are the cause of hereditary hemorrhagic telangiectasia type 1 (HHT1).
Alternate Names: CD105, Endoglin, ENG, END
Application Notes: Cat. No. 254549 corresponds to CD105 Antibody (Cat. No. 251222) conjugated to Cy3 dye. FC: 1:20-1:100; Ex: 512-550 nm, Em: 570-615 nm
Accession No.: P17813
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human CD105.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 0.1 mg/ml BSA, 50% glycerol with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography.
Storage:
Store at 4°C. Product is guaranteed 6 months from the date of shipment.
Pathway and Disease: Signaling Molecules and Interaction
Description:
The CD105 antigen (endoglin) is a major glycoprotein of the vascular endothelium with a role in integrins and RGD receptors for endothelial cell adhesion. CD105 forms heteromeric complex with signaling receptors for transforming growth factor-beta. CD105 expression is restricted to endothelial cells in all tissues except bone marrow. Defects in CD105 are the cause of hereditary hemorrhagic telangiectasia type 1 (HHT1).
Alternate Names: CD105, Endoglin, ENG, END
Application Notes: Cat. No. 254549 corresponds to CD105 Antibody (Cat. No. 251222) conjugated to Cy3 dye. FC: 1:20-1:100; Ex: 512-550 nm, Em: 570-615 nm
Accession No.: P17813
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human CD105.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 0.1 mg/ml BSA, 50% glycerol with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography.
Storage:
Store at 4°C. Product is guaranteed 6 months from the date of shipment.
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