CD105 polyclonal (Center E395), anti-human, mouse

CD105 polyclonal (Center E395), anti-human, mouse

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In stock
SKU
AC-AP2880C
Catalog Number: AC-AP2880C
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB17987
Applications: WB, FC, IHC-P
Datasheet

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Background:
CD105 is a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds TGFB1 and TGFB3 with high affinity. Mutations in its gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia.

Other Names:
Endoglin, CD105, ENG, END

Target/Specificity:
This CD105 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 380-409 amino acids from the Central region of human CD105.

Antigen Region:
380-409

Antigen Type: Synthetic Peptide

Gene Name: ENG
Gene ID: 2022
Primary Accession: P17813
NCBI Accession: NP_000109.1;NP_001108225.1;NP_001265067.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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