CD106 (VCAM-1) polyclonal, anti-human, mouse, rat

Protein Family: CAM Ligands, Cell Adhesion Molecules, Cellular Antigens, Glycan Binding Proteins

Pathway and Disease: Immune System, Signaling Molecules and Interaction

Description:
Vascular cell adhesion molecule 1 (VCAM-1) is a member of the Ig superfamily that plays an important role in cell-cell recognition. VCAM-1 interacts with beta-1 integrin (VLA4) on leukocytes to mediate adhesion and signal transduction during leukocyte-endothelial cell adhesion. VCAM-1 is likely involved in atherosclerosis and rheumatoid arthritis.

Alternate Names: Vascular cell adhesion protein 1, V-CAM1, INCAM-100, CD106 antigen, VCAM1, L1CAM

Application Notes: E: 1:500-1:1,000; WB: 1:200-1:500; IHC: 1:200-1:500

Accession No.: P19320

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human VCAM-1.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 25% glycerol, 5 mg/ml BSA with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.

Product Citations:
Day R et al.2013. American Journal of Physiology-Renal Physiology. 304(6):F788-F800. PMID# 23303408.