CD107a (LAMP1) polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
LAMP1(lysosomal-associated membrane protein 1) also called LAMPA, LGP120 or CD107A, is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. It may also play a role in tumor cell metastasis. CD107a has also been shown to be a marker of degranulation on lymphocytes such as CD8+ and NK cells. By means of in situ hybridization, Mattei et al.(1990) assigned the LAMP1 gene to chromosome 13q34. A related gene, which may be a pseudogene, mapped to chromosome 12p13.3. Hybridization of LAMP1 cDNA to chromosome 12p13.3 was observed even when probes representing different portions of the LAMP1 cDNA were used.

Description:
Rabbit IgG polyclonal antibody for Lysosome-associated membrane glycoprotein 1 (LAMP1) detection. Tested with WB in Human, Mouse, Rat.

Synonyms:
CD107 antigen like family member A antibody, CD107 antigen-like family member A antibody, CD107a antibody, CD107a antigen antibody, LAMP 1 antibody, LAMP-1 antibody, LAMP1 antibody, LAMP1_HUMAN antibody, LAMPA antibody, LGP120 antibody, lgpA antibody, Lysosomal membrane glycoprotein 120KD antibody, Lysosomal Associated Membrane Protein 1 antibody, Lysosome associated membrane glycoprotein 1 antibody, Lysosome-associated membrane glycoprotein 1 antibody, Lysosome-associated membrane protein 1 antibody, OTTHUMP00000040663 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human LAMP1(403-417aa YLVGRKRSHAGYQTI), different from the related mouse and rat sequences by one amino acid.A synthetic peptide corresponding to a sequence at the C-terminus of human LAMP1(403-417aa YLVGRKRSHAGYQTI), different from the related mouse and rat sequences by one amino acid.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, rat .
Predicted to work with: mouse.

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.