MEF-2 (phospho Ser408) polyclonal, anti-human, mouse, rat
€470.00
In stock
SKU
AC-AP67792
Catalog Number: AC-AP73894
Size: 100 µl
Host: Rabbit
Applications: WB, IHC-P
Datasheet
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Size: 100 µl
Host: Rabbit
Applications: WB, IHC-P
Datasheet
Request Information
Background:
Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT](4)TAR-3', found in numerous muscle- specific genes. Also involved in the activation of numerous growth factor- and stress-induced genes. Mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival. Plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription. In cerebellar granule neurons, phosphorylated and sumoylated MEF2A represses transcription of NUR77 promoting synaptic differentiation. Associates with chromatin to the ZNF16 promoter.
Other Names:
MEF2A; MEF2; Myocyte-specific enhancer factor 2A; Serum response factor-like protein 1
Antigen Type: synthetic peptide
Antigen Type: MEF2A
Gene ID: 4205
Primary Accession: Q02078
Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT](4)TAR-3', found in numerous muscle- specific genes. Also involved in the activation of numerous growth factor- and stress-induced genes. Mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival. Plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription. In cerebellar granule neurons, phosphorylated and sumoylated MEF2A represses transcription of NUR77 promoting synaptic differentiation. Associates with chromatin to the ZNF16 promoter.
Other Names:
MEF2A; MEF2; Myocyte-specific enhancer factor 2A; Serum response factor-like protein 1
Antigen Type: synthetic peptide
Antigen Type: MEF2A
Gene ID: 4205
Primary Accession: Q02078
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