CD11a (Integrin alphaL,LFA-1 alpha Chain) (clone CRIS-3), anti-human

CD11a (Integrin alphaL,LFA-1 alpha Chain) (clone CRIS-3), anti-human

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In stock
SKU
ARP-24-3683-MSM1
Catalog Number: 24-3683-MSM1
Size: 100 µl, 0.5 ml, 1 ml
Isotype: Mouse IgG2b kappa
Decription:
Recognizes a protein of 180kDa, identified as CD11a (Leucocyte Workshop II; Code N202). CD11a complex with the 2 subunit of the integrin family, CD18, to form the cell surface heterodimer, LFA-1 or CD11a /C18 (aLbL). LFA-1 is expressed on all leukocytes including lymphocytes, monocytes, and granulocytes. It is involved in leukocyte adhesion to its ligands including intercellular adhesion molecule-1 (ICAM-1 or CD54), ICAM-2 (CD102), ICAM-3 (CD50) and Telencephalin (TLN) and play a role in most immune/inflammatory responses.

Synonyms: Antigen CD11A (p180), lymphocyte function associated antigen 1, alpha polypeptide, Integrin alpha-L, ITGAL, Leukocyte Adhesion Glycoprotein LFA1 Alpha Chain, LFA 1 alpha (LFA1A), Ly15, Ly21, p180

Clone: CRIS-3

Isotype: Mouse IgG2b kappa

Immunogen: Stimulated human leukocytes

Reactivity: human. Others not known.

Form: Purified, in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Applications: Flow Cytometry (0.5-1ug/million cells in 0.1ml)
Immunofluorescence (0.5-1ug/ml)
Functional Studies (Order Ab without BSA & Azide)
Optimal dilution for a specific application should be determined.

Reactivity: JY, HUT-78, MOLT-4, HL60, U937, and human leukocytes. Human lymph nodes and tonsils.

Concentration: 0.2mg/ml

Storage: Can be stored at +4C. For long term storage, aliquot and store at -20C. Avoid repeated freezing and thawing cycles.
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