CD11B polyclonal, anti-human

Background:
CD11b is the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles.

Synonyms: ITGAM, CD11B, CR3A

Cellular Location: Cell membrane Membrane

Immunogen:
A synthetic peptide of human CD11B

Gene Symbol: CD11B

Gene ID: 3684

Swiss prot: P11215

Calculated MW: 180kDa

Recommended dilution:
WB 1:2000, IHC 1:25, FC 1:10-50,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.