CD11b polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
Integrin alpha M (ITGAM) is one protein subunit that forms the heterodimeric integrin alpha-M beta-2 (αMβ2) molecule, also known as macrophage-1 antigen (Mac-1) or complement receptor 3 (CR3). It is mapped to 16p11.2. ITGAM has a role in vascular repair after mechanical arterial injury. It is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. What's more, ITGAM probably recognizes the R-G-D peptide in C3b, and it is also a receptor for fibrinogen, factor X and ICAM1.

Description:
Rabbit IgG polyclonal antibody for Integrin alpha-M (ITGAM) detection. Tested with WB, IHC-P in Human, Mouse, Rat.

Synonyms:
Antigen CD11b p170 antibody, CD11 antigen like family member B antibody, CD11 antigen-like family member B antibody, CD11b antibody, CD11b/CD18 antibody, CD49d antibody, Cell surface glycoprotein MAC-1 subunit alpha antibody, Complement component 3 receptor 3 subunit antibody, Complement Component Receptor 3 Alpha antibody, Complement receptor type 3, alpha subunit antibody, CR 3 alpha chain antibody, CR-3 alpha chain antibody, CR3 antibody, CR3A antibody, F730045J24Rik antibody, Integrin Alpha M antibody, Integrin alpha M chain antibody, Integrin alpha-M antibody, Integrin beta 2 alpha subunit antibody, ITAM_HUMAN antibody, ITGAM antibody, Leukocyte adhesion receptor MO1 antibody, Ly-40 antibody, MAC 1 antibody, Mac-1a antibody, MAC1 antibody, Mac1, alpha subunit antibody, MAC1A antibody, Macrophage antigen alpha polypeptide antibody, MGC117044 antibody, Mo1, alpha subunit antibody, MO1A antibody, Neutrophil adherence receptor alpha M subunit antibody, Neutrophil adherence receptor antibody, SLEB6 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
E.coli-derived human CD11b recombinant protein (Position: F17-T382). Human CD11b shares 79% and 61% amino acid (aa) sequences identity with mouse and rat CD11b, respectively.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, mouse, rat

Applications: WB, IHC-P

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.