CD120b (TNF Receptor II) polyclonal, anti-mouse, rat

Quantity: 100 µg

Background:
TNFRSF1B(Tumor Necrosis Factor Receptor Subfamily Member 1B), also known as TNFR2 or TNFBR, is a protein that in humans is encoded by the TNFRSF1B gene. The protein encoded by this gene is a member of the Tumor necrosis factor receptor superfamily, which also contains TNFRSF1A. By linkage analysis, Santee and Owen Schaub(1996) confirmed the mapping of the TNFR2 gene to 1p36.3-p36.2. TNFBR(TNFR75) is the larger of the 2 TNF receptors. It is present on many cell types, especially those of myeloid origin, and is strongly expressed on stimulated T and B lymphocytes. Beltinger et al.(1996) noted that TNFR2 is the main TNF receptor found on circulating T cells and is the major mediator of autoregulatory apoptosis in CD8+ cells. TNFR2 may act with TNFR1 to kill nonlymphoid cells.

Description:
Rabbit IgG polyclonal antibody for Tumor necrosis factor receptor superfamily member 1B (TNFRSF1B) detection. Tested with WB in Mouse, Rat.

Synonyms:
CD 120b antibody, CD120b antibody, CD120b antigen antibody, Etanercept antibody, p75 antibody, p75TNFR antibody, p80 TNF alpha receptor antibody, p80 TNF-alpha receptor antibody, TBP-2 antibody, TBP2 antibody, TBPII antibody, TNF R II antibody, TNF R2 antibody, TNF R75 antibody, TNF-R2 antibody, TNF-RII antibody, TNFBR antibody, TNFR 2 antibody, TNFR-II antibody, TNFR2 antibody, TNFR75 antibody, TNFR80 antibody, TNFRII antibody, TNFRSF 1B antibody, TNFRSF1B antibody, TNR1B antibody, TNR1B_HUMAN antibody, Tumor necrosis factor beta receptor antibody, Tumor necrosis factor binding protein 2 antibody, Tumor necrosis factor receptor 2 antibody, Tumor necrosis factor receptor superfamily member 1B precursor antibody, Tumor necrosis factor receptor type II antibody, Tumor necrosis factor-binding protein 2 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the N-terminus of mouse TNF Receptor II(38-55aa YECQISQEYYDRKAQMCC), different from the related rat sequence by three amino acids.A synthetic peptide corresponding to a sequence at the N-terminus of mouse TNF Receptor II(38-55aa YECQISQEYYDRKAQMCC), different from the related rat sequence by three amino acids.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: mouse, rat

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.