CD122 (IL2RB) polyclonal, anti-mouse

Quantity: 100 µg

Background:
IL2RB (INTERLEUKIN 2 RECEPTOR, BETA), also called CD122, is a protein that in humans is encoded by the IL2RB gene. The gene represents the beta subunit and is a type I membrane protein. IL2RB is mapped to 22q12.3. The IL2RB gene contains 10 exons spanning about 24.3 kb and that the gene product is encoded by exons 2-10. The IL2 receptor is present in 3 forms with respect to binding ability to IL2: high, intermediate, and low affinity forms. Analysis of mutants of the beta chain of the IL2 receptor reveals that the granulocyte and monocyte differentiation signals are triggered by different cytoplasmic domains, showing that the signaling pathways responsible for these unique developmental outcomes are separable.

Description:
Rabbit IgG polyclonal antibody for Interleukin-2 receptor subunit beta (IL2RB) detection. Tested with WB in Mouse.

Synonyms:
CD 122 antibody, CD122 antibody, CD122 antigen antibody, High affinity IL 2 receptor beta subunit antibody, High affinity IL 2 receptor subunit beta antibody, High affinity IL-2 receptor subunit beta antibody, High affinity IL2 receptor beta subunit antibody, High affinity IL2 receptor subunit beta antibody, IL 2 receptor antibody, IL-2 receptor subunit beta antibody, IL-2R subunit beta antibody, IL-2RB antibody, IL15RB antibody, IL2 R B antibody, IL2 RB antibody, IL2 receptor antibody, IL2RB antibody, IL2RB_HUMAN antibody, Interleukin 2 receptor beta antibody, Interleukin 2 receptor subunit beta antibody, Interleukin-2 receptor subunit beta antibody, OTTHUMP00000028799 antibody, P70 75 antibody, P70-75 antibody, P7075 antibody, p75 antibody.

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of mouse IL2RB (503-539aa NLHGQDQDRGQGPILTLNTDAYLSLQELQAQDSVHLI), different from the related human sequence by sixteen amino acids, and from the related rat sequence by fourteen amino acids.A synthetic peptide corresponding to a sequence at the C-terminus of mouse IL2RB (503-539aa NLHGQDQDRGQGPILTLNTDAYLSLQELQAQDSVHLI), different from the related human sequence by sixteen amino acids, and from the related rat sequence by fourteen amino acids.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: mouse

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.