CD123 (IL-3RA) polyclonal, anti-human

Quantity: 100 µg

Background:
IL3RA(INTERLEUKIN 3 RECEPTOR, ALPHA), also called CD123(Cluster of Differentiation 123), is a human gene. The protein encoded by this gene is an interleukin 3 specific subunit of a heterodimeric cytokine receptor which is composed of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3(IL3), colony stimulating factor 2(CSF2/GM-CSF), and interleukin 5(IL5). The IL3RA is mapped on Xp22.33. The genomic structures of IL3RA and CSF2RA are very similar and share an additional exon encoding part of the C-terminal domain not found in other members of this gene family. As in human hematopoietic cells, IL3 and GMCSF competed for binding in fibroblasts expressing the cDNAs for IL3RA, CSF2RA, and the common beta subunit, indicating that different alpha subunits compete for a common beta subunit.

Description:
Rabbit IgG polyclonal antibody for Interleukin-3 receptor subunit alpha (IL3RA) detection. Tested with WB in Human.

Synonyms:
CD123 antibody, CD123 antigen antibody, hIL 3Ra antibody, hIL-3Ra antibody, hIL3Ra antibody, IL 3 receptor alpha SP2 isoform antibody, IL 3R alpha antibody, IL-3 receptor subunit alpha antibody, IL-3R subunit alpha antibody, IL-3R-alpha antibody, IL-3RA antibody, IL3 Receptor alpha antibody, IL3R antibody, IL3Ra antibody, IL3RA_HUMAN antibody, IL3RAX antibody, IL3RAY antibody, IL3RX antibody, IL3RY antibody, Interleukin 3 receptor alpha chain antibody, Interleukin 3 receptor, alpha(low affinity) antibody, Interleukin 3 receptor, alpha antibody, Interleukin-3 Receptor alpha antibody, Interleukin-3 receptor subunit alpha antibody, Interleukin3 receptor antibody, Interleukin3 receptor, Y-chromosomal antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence in the middle region of human IL3RA(135-151aa QYDLYLNVANRRQQYEC).

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.