CD125 (IL-5RA) polyclonal, anti-human

Quantity: 100 µg

Background:
IL5RA(INTERLEUKIN 5 RECEPTOR, ALPHA), also known as CD125, is a subunit of the Interleukin-5 receptor. IL5RA also denotes its human gene. The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor which is composed of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3(IL3), colony stimulating factor 2(CSF2/GM-CSF), and interleukin 5(IL5). The IL5RA gene is mapped to 3p26-p24 by Southern blot analysis of DNA from a panel of mouse-human hybrid somatic cell lines complemented by in situ hybridization. And its Cytogenetic location is 3p26.2. Within this 15-residue stretch of IL5RA, the C-terminal phenylalanine is critical. The binding of this protein to IL5 depends on the beta subunit which is activated by the ligand binding and is required for the biological activities of IL5.

Description:
Rabbit IgG polyclonal antibody for Interleukin-5 receptor subunit alpha (IL5RA) detection. Tested with WB in Human.

Synonyms:
CD125 antibody, CD125 antigen antibody, CDw125 antibody, HSIL5R3 antibody, IL-5 receptor subunit alpha antibody, IL-5R subunit alpha antibody, IL-5R-alpha antibody, IL-5RA antibody, IL5R antibody, IL5RA antibody, IL5RA_HUMAN antibody, Interleukin 5 Receptor alpha antibody, Interleukin 5 Receptor alpha chain antibody, Interleukin 5 receptor alpha subunit antibody, Interleukin 5 receptor subunit alpha antibody, Interleukin 5 receptor type 3 antibody, Interleukin-5 receptor subunit alpha antibody, MGC26560 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the N-terminus of human IL5RA(53-68aa NPDQEQRNVNLEYQVK).

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.