CD127 Polyclonal Antibody

Background:
The protein encoded by this gene is a receptor for interleukin 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukins 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in V(D)J recombination during lymphocyte development. Defects in this gene may be associated with severe combined immunodeficiency (SCID). Alternatively spliced transcript variants have been found.

Research Area: Cancer, Immunology, Stem Cells

Synonyms:
IL7R, CD127, CDW127, IL-7R-alpha, IL7RA, ILRA

Immunogen: Recombinant fusion protein of human CD127 (NP_002176.2).

Swissprot: P16871
Gene ID: 3575

Calculated MW: 28 kDa/29 kDa/34 kDa/51 kDa
Observed MW: 75 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000 IF 1:20-1:50"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.