CD130 polyclonal, anti-human, mouse, rat
€295.00
In stock
SKU
K106480P
Catalog Number: K106480P
Size: 100 μl
Other size: 50 μl
Isotype: RabbitIgG
Applications: WB
Request Manual
Questions? Contact us!
Size: 100 μl
Other size: 50 μl
Isotype: RabbitIgG
Applications: WB
Request Manual
Questions? Contact us!
Background:
The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggest that this gene plays a critical role in regulating myocyte apoptosis. Alternatively spliced transcript variants have been described. A related pseudogene has been identified on chromosome 17.
Synonyms: CDW130, GP130, IL-6RB, IL6ST, IL-6R beta
Cellular Location: Cell membrane Nucleus Extracellular matrix
Immunogen:
A synthetic peptide of human CD130
Gene Symbol: CD130
Gene ID: 3572
Swiss prot: P40189
Calculated MW: 65/125kDa
Recommended dilution:
WB 1:3000
Purity:
Affinity purification
Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
Storage:
Store at -20℃. Avoid freeze / thaw cycles.
The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggest that this gene plays a critical role in regulating myocyte apoptosis. Alternatively spliced transcript variants have been described. A related pseudogene has been identified on chromosome 17.
Synonyms: CDW130, GP130, IL-6RB, IL6ST, IL-6R beta
Cellular Location: Cell membrane Nucleus Extracellular matrix
Immunogen:
A synthetic peptide of human CD130
Gene Symbol: CD130
Gene ID: 3572
Swiss prot: P40189
Calculated MW: 65/125kDa
Recommended dilution:
WB 1:3000
Purity:
Affinity purification
Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
Storage:
Store at -20℃. Avoid freeze / thaw cycles.
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