CD130 rabbit polyclonal, anti-human, mouse

Backgroud: The receptor systems for IL6, LIF, OSM, CNTF, IL11, CTF1 and BSF3 can utilize IL6ST for initiating signal transmission. Binding of IL6 to IL6R induces IL6ST homodimerization and formation of a high-affinity receptor complex, which activates the intracellular JAK-MAPK and JAK-STAT3 signaling pathways.

Synonyms: Interleukin-6 receptor subunit beta ,IL-6 receptor subunit beta,IL-6R subunit beta,IL-6R-beta, IL-6RB,CDw130

Gene Name: IL6ST

Gene ID: 3572

SwissProt ID: P40189

Purification: Affinity Purified

Storage: Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.