CD132 (IL-2Rgamma) polyclonal, anti-human

Quantity: 100 µg

Background:
IL2RG(INTERLEUKIN 2 RECEPTOR, GAMMA),also known as Common gamma chain or CD132, is a cytokine receptor sub-unit that is common to the receptor complexes for at least six different interleukin receptors:IL-2, IL-4, IL-7, IL-9, IL-15 and interleukin-21 receptor. IL2RG is a member of the type I cytokine receptor family expressed on most lymphocyte(white blood cell) populations, and its gene is found on the X-chromosome of mammals. By fluorescence in situ hybridization and PCR amplification of somatic cell hybrid DNAs, The IL2RG gene is mapped to Xq13.1. The IL2RG gene contains 8 exons and spans approximately 4.2 kb. And the gamma chain is an indispensable component of the functional IL2 receptor. Lymphocytes expressing the common gamma chain can form functional receptors for these cytokine proteins, which transmit signals from one cell to another and direct programs of cellular differentiation. The sharing of the gamma subunit by several receptors explains why humans and mice that lack IL2 entirely show milder symptoms than those with IL2RG deficiency.

Description:
Rabbit IgG polyclonal antibody for Cytokine receptor common subunit gamma (IL2RG) detection. Tested with WB in Human.

Synonyms:
CD132 antibody, common cytokine receptor gamma chain antibody, Cytokine receptor common subunit gamma antibody, Gamma C antibody, gamma(c) antibody, gammaC antibody, IL-2 receptor subunit gamma antibody, IL-2R gamma chain antibody, IL-2R subunit gamma antibody, IL-2RG antibody, Il2rg antibody, IL2RG_HUMAN antibody, IMD4 antibody, interleukin 2 receptor, gamma antibody, Interleukin-2 receptor subunit gamma antibody, p64 antibody, SCIDX antibody, SCIDX1 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence in the middle region of human IL2 Receptor gamma(88-102aa HYWYKNSDNDKVQKC).

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.