CD133 (PROM1) polyclonal, anti-human

Quantity: 100 µg

Background:
Prominin-1, also known as CD133, is a glycoprotein that in humans is encoded by the PROM1 gene. It is mapped to 4p15.32. Prominin-1 is a member of pentaspan transmembrane glycoproteins (5-transmembrane, 5-TM), which specifically localize to cellular protrusions. This gene encodes a pentaspan transmembrane glycoprotein. The protein localizes to membrane protrusions and is often expressed on adult stem cells, where it is thought to function in maintaining stem cell properties by suppressing differentiation. It has been proposed to act as an organizer of cell membrane topology. Prominin-1 was expressed not only on metastatic colon cancer cells, but also on differentiated colonic epithelium in both adult mice and humans.

Description:
Rabbit IgG polyclonal antibody for Prominin-1 (PROM1) detection. Tested with WB, IHC-P in Human.

Synonyms:
AC133, Antigen AC133, CD133 antibody, CORD12, hematopoietic stem cell antigen, hProminin, MCDR2, MSTP061 antibody, PROM1, PROM 1, PROM-1, Prominin-1, Prominin 1, Prominin1, Prominin-like protein 1, PROML1 antibody, RP41, STGD4

Isotype: Rabbit polyclonal IgG

Immunogen:
E.coli-derived human PROM1 recombinant protein (Position: P531-H865). Human PROM1 shares 61% amino acid (aa) sequence identity with mouse PROM1.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human

Applications: WB, IHC-P

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.