CD133 (PROM1) polyclonal, anti-human, rat

Quantity: 100 µg

Background:
PROM1(Prominin 1), also called CD133, is a glycoprotein. Maw et al.(2000) noted that D4S1601 and D4S3048, which are located on human chromosome 4p15.3-p15.2, map within intronic sequences of the PROML1 gene. Torrente et al.(2004) reported that a subpopulation of circulating cells expressing AC133, a well-characterized marker of hematopoietic stem cells, also expresses early myogenic markers. Singh et al.(2003) prospectively isolated a CD133-positive cell subpopulation from human brain tumors that exhibited stem cell properties in vitro. However, the true measures of cancer stem cells are their capacity for self renewal and exact recapitulation of the original tumor.

Description:
Rabbit IgG polyclonal antibody for Prominin-1 (PROM1) detection. Tested with WB, IHC-P in Human, Rat.

Synonyms:
AC133 antibody, Antigen AC133 antibody, CD133 antibody, CORD12 antibody, hematopoietic stem cell antigen antibody, hProminin antibody, MCDR2 antibody, MSTP061 antibody, PROM1 antibody, PROM 1 antibody, PROM-1 antibody, Prominin-1 antibody, Prominin 1 antibody, Prominin1 antibody, Prominin-like protein 1 antibody, PROML1 antibody, RP41 antibody, STGD4 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human PROM1(836-850aa MKNMENGNNGYHKDH), different from the related rat sequence by two amino acids, and from the related mouse sequence by three amino acids.A synthetic peptide corresponding to a sequence at the C-terminus of human PROM1(836-850aa MKNMENGNNGYHKDH), different from the related rat sequence by two amino acids, and from the related mouse sequence by three amino acids.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, rat

Applications: WB, IHC-P

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.