CD134/OX40 (clone ), anti-human, mouse, rat

Background:
Ox40 (also designated CD134 and Ox40R), is a member of the tumor necrosis factor receptor (TNFR) family. Ox40 is involved in coordinating CD4 T cell selection, migration and cytokine differentiation in T helper (Th)1 and Th2 cells. Ox40 is also involved in the stimulation of T cells, T cell-dependent humoral response and generation of optimal CD4+ T cell responses in vivo and in vitro. Ox40 is expressed on activated CD4+ T lymphocytes and its ligand, Ox40L, is found preferentially on activated B cells. Engagement of Ox40 with its ligand, Ox40L, delivers a strong costimulatory signal to effector T cells. Members of the TNFR superfamily are critically involved in the regulation of infections, inflammation, autoimmune diseases and tissue homeostasis.

Alternative Name:
TNFRSF4, TXGP1L, ACT 35, ACT35, ACT35 antigen, ATC35 antigen, CD 134, CD134, CD134 antigen, IMD16, Lymphoid activation antigene ACT35, OX 40, OX40, OX40 antigen, OX40 cell surface antigen, OX40 homologue, OX40L receptor, TAX transcriptionally activated glycoprotein 1 receptor, TAX transcriptionally-activated glycoprotein 1 receptor, TNF receptor superfamily member 4, TNFRSF 4, TNFRSF4, TNR4, Tumor necrosis factor receptor superfamily member 4, Txgp 1l, Txgp1, Txgp1l,

Application Dilution:
WB:1:500
ICC:1:50-1:200
IHC:1:50-1:200
FC:1:50-1:100

Specificity: CD134/OX40 monoclonal antibody detects endogenous levels of CD134/OX40 protein.

Immunogen:
Recombinant protein

MW: 55 kDa

Swiss-Prot: P43489(Human) P47741(Mouse) P15725(Rat)

Purification & Purity:
ProA affinity purified

Format:
Mouse IgG1, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Storage:
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

For research use only, not for use in diagnostic procedure.