CD137 (clone M4173), anti-mouse

Decription:
CD137 is a member of the tumor necrosis factor (TNF) receptor family. CD137 is expressed by activated T cells, dendritic cells, NK cells, granulocytes and cells of blood vessel walls at sites of inflammation. CD137 has costimulatory activity for activated T cells. Crosslinking of CD137 enhances T cell proliferation, IL-2 secretion survival and cytolytic activity. CD137 was shown to enhance immune activity to eliminate tumors in mice.

Synonyms: 4-1BB, TNFRSF9

Clone: M4173

Isotype: Rat IgG1 kappa

Immunogen: Recombinant mouse CD137.

Reactivity: mouse

Specificity: Recognizes mouse CD137. Detects a band of ~40kDa by Western blot. Does not cross-react with human CD137.

Form: Purified, in 0.2um-filtered solution in PBS, pH 7.4. Contains no preservatives.

Applications:
Flow Cytometry: (1:500)
Western Blot: (1:2'000)

Working Dilution: Optimal conditions must be determined individually for each application.

Concentration: 1mg/ml

Storage: 2-8C immediate use, or -20C (aliquote)