CD138 monoclonal (C-term) (Ascites), anti-human

Background:
The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein.

Other Names:
Syndecan-1, SYND1, CD138, SDC1, SDC

Target/Specificity:
This CD138 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 210-238 amino acids from the C-terminal region of human CD138.

Antigen Region:
210-238

Antigen Type: Synthetic Peptide

Gene Name: SDC1 (HGNC:10658)
Gene ID: 6382
Primary Accession: P18827
NCBI Accession: NP_001006947.1;NP_002988.3
Other Accession: NP_001006947.1
Format: Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.