CD138 (Syndecan-1) polyclonal, anti-human

Quantity: 100 µg

Background:
Syndecan 1 is a protein which in humans is encoded by the SDC1 gene. The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein.

Description:
Rabbit IgG polyclonal antibody for Syndecan-1 (SDC1) detection. Tested with WB in Human.

Synonyms:
CD_antigen antibody, CD138 antibody, CD138 antigen antibody, heparan sulfate proteoglycan fibroblast growth factor receptor antibody, SDC antibody, Sdc1 antibody, SDC1_HUMAN antibody, SYND1 antibody, Syndecan 1 antibody, syndecan proteoglycan 1 antibody, Syndecan-1 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human Syndecan-1 (218-251aa ENTAVVAVEPDRRNQSPVDQGATGASQGLLDRKE), different from the related mouse sequence by six amino acids, and from the related rat sequence by four amino acids.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.