CD14 (clone 5A3), anti-human
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In stock
SKU
BT-MCA3857
Catalog Number: BT-MCA3857
Size(s): 50μL, 100μL
Isotype: Mouse IgG1
Reactivity: human
Application(s): IHC, FCM
Datasheet
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Size(s): 50μL, 100μL
Isotype: Mouse IgG1
Reactivity: human
Application(s): IHC, FCM
Datasheet
Request Information
Background:
CD14 antigen is a GPI-linked glycoprotein with a molecular weight of 55kD. The CD14 antigen is expressed on cells of the myelomonocytic lineage including monocytes, macrophages and Langerhans cells. Low expression is observed on neutrophils and on human B cells. CD14 antigen is a receptor for bacterial lipopolysaccharide (LPS, endotoxin) and the lipopolysaccharide binding protein (LBP). LBP and CD14 antigen serves two physiological roles. These proteins act as opsonin and opsonic receptor, respectively, to promote the phagocytic uptake of bacteria or LPScoated particles by macrophages.
Research Area: Immunology, Stem cells
Synonyms: CD14
Immunogen: Purified recombinant fragment of human CD14 expressed in E. Coli.
Formulation: Ascitic fluid containing 0.03% sodium azide.
Storage:
4°C|-20°C for long term storage
CD14 antigen is a GPI-linked glycoprotein with a molecular weight of 55kD. The CD14 antigen is expressed on cells of the myelomonocytic lineage including monocytes, macrophages and Langerhans cells. Low expression is observed on neutrophils and on human B cells. CD14 antigen is a receptor for bacterial lipopolysaccharide (LPS, endotoxin) and the lipopolysaccharide binding protein (LBP). LBP and CD14 antigen serves two physiological roles. These proteins act as opsonin and opsonic receptor, respectively, to promote the phagocytic uptake of bacteria or LPScoated particles by macrophages.
Research Area: Immunology, Stem cells
Synonyms: CD14
Immunogen: Purified recombinant fragment of human CD14 expressed in E. Coli.
Formulation: Ascitic fluid containing 0.03% sodium azide.
Storage:
4°C|-20°C for long term storage
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