CD14 polyclonal, anti-mouse

Quantity: 100 µg

Background:
CD14, Cluster of differentiation 14, single-copy gene encoding 2 protein forms: a 50- to 55-kD glycosylphosphatidylinositol-anchored membrane protein(mCD14) and a monocyte or liver-derived soluble serum protein(sCD14) that lacks the anchor. By in situ hybridization and study of somatic cell hybrid DNA that the gene is located at bands 5q23-q31. CD14 acts as a co-receptor(along with the Toll-like receptor TLR 4 and MD-2) for the detection of bacterial lipopolysaccharide(LPS). CD14 can bind LPS only in the presence of lipopolysaccharide-binding protein(LBP). Although LPS is considered its main ligand, CD14 also recognizes other pathogen-associated molecular patterns.

Description:
Rabbit IgG polyclonal antibody for Monocyte differentiation antigen CD14 (CD14) detection. Tested with WB in Mouse.

Synonyms:
CD 14 antibody, CD_antigen=CD14 antibody, CD14 antibody, CD14 antibody, CD14 antigen antibody, CD14 molecule antibody, CD14_HUMAN antibody, LPS-R antibody, Mo2 antibody, Monocyte differentiation antigen CD14 antibody, Monocyte differentiation antigen CD14 urinary form antibody, Monocyte differentiation antigen CD14, membrane-bound form antibody, Myeloid cell specific leucine rich glycoprotein antibody, Myeloid cell-specific leucine-rich glycoprotein antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence in the middle region of mouse CD14(152-165aa TRDAWLAELQQWLK).A synthetic peptide corresponding to a sequence in the middle region of mouse CD14(152-165aa TRDAWLAELQQWLK).

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: mouse

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.