CD143 (Angiotensin Converting Enzyme 1) polyclonal, anti-human

Quantity: 100 µg

Background:
Angiotensin I converting enzyme(ACE), also called DCP or CD143, is a zinc-containing dipeptidyl carboxypeptidase widely distributed in mammalian tissues and is though to play a critical role in blood pressure regulation. ACE gene is mapped to 17q23.3. This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies.

Description:
Rabbit IgG polyclonal antibody for Angiotensin-converting enzyme (ACE) detection. Tested with WB, IHC-P in Human.

Synonyms:
ACE 1 antibody, ACE antibody, ACE T antibody, ACE_HUMAN antibody, ACE1 antibody, Angiotensin converting enzyme somatic isoform antibody, Angiotensin converting enzyme testis specific isoform antibody, Angiotensin I converting enzyme 1 antibody, Angiotensin I converting enzyme antibody, Angiotensin I converting enzyme peptidyl dipeptidase A 1 antibody, Angiotensin-converting enzyme antibody, Carboxycathepsin antibody, CD 143 antibody, CD143 antibody, CD143 antigen antibody, DCP 1 antibody, DCP antibody, DCP1 antibody, Dipeptidyl carboxypeptidase 1 antibody, Dipeptidyl carboxypeptidase I antibody, Kininase II antibody, MGC26566 antibody, MVCD3 antibody, Peptidase P antibody, Peptidyl dipeptidase A antibody, soluble form antibody, Testicular ECA antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence in the middle region of human Angiotensin Converting Enzyme 1(702-715aa TQARKFDVNQLQNT).

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human

Applications: WB, IHC-P

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.