CD147 (EMMPRIN, Neurothelin) (clone CB43), anti-human
€0.00
In stock
SKU
ARP-24-682-MSM2
Catalog Number: 24-682-MSM2
Size: 100 µl, 0.5 ml, 1 ml
Isotype: Mouse IgM
Size: 100 µl, 0.5 ml, 1 ml
Isotype: Mouse IgM
Decription:
CD147 is a transmembrane glycoprotein of the immunoglobulin superfamily. It is expressed more intensely on thymocytes than on mature peripheral blood T cells. CD147 is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. CD147 is involved in the regulation of matrix remodeling at the epidermal-dermal interface. It stimulates the production of interstitial collagenase, gelatinase A, stromelysin-1 and various metalloproteinases (MMPs) by fibroblasts. These enzymes, which are typically increased during tissue degradation and wound healing, are important factors in cancer invasion and metastasis.
Synonyms: 5A11 Antigen, 5F7, Basigin, Blood brain barrier HT7 antigen BSG, Emmprin, Extracellular Matrix Metalloproteinase Inducer, Leukocyte Activation Antigen M6, Neurothelin, OK Blood Group Antigen, TCSF, Tumor Cell-derived Collagenase Stimulatory Factor
Clone: CB43
Isotype: Mouse IgM
Immunogen: Native human leucocytes
Reactivity: human. Others not known.
Form: Purified, in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Applications: Flow Cytometry (0.5-1ug/million cells in 0.1ml)
Immunofluorescence (0.5-1ug/ml)
Optimal dilution for a specific application should be determined.
Reactivity: HSB2 cells. Renal Cell, Ovarian carcinoma or Melanoma
Concentration: 0.2mg/ml
Storage: Can be stored at +4C. For long term storage, aliquot and store at -20C. Avoid repeated freezing and thawing cycles.
CD147 is a transmembrane glycoprotein of the immunoglobulin superfamily. It is expressed more intensely on thymocytes than on mature peripheral blood T cells. CD147 is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. CD147 is involved in the regulation of matrix remodeling at the epidermal-dermal interface. It stimulates the production of interstitial collagenase, gelatinase A, stromelysin-1 and various metalloproteinases (MMPs) by fibroblasts. These enzymes, which are typically increased during tissue degradation and wound healing, are important factors in cancer invasion and metastasis.
Synonyms: 5A11 Antigen, 5F7, Basigin, Blood brain barrier HT7 antigen BSG, Emmprin, Extracellular Matrix Metalloproteinase Inducer, Leukocyte Activation Antigen M6, Neurothelin, OK Blood Group Antigen, TCSF, Tumor Cell-derived Collagenase Stimulatory Factor
Clone: CB43
Isotype: Mouse IgM
Immunogen: Native human leucocytes
Reactivity: human. Others not known.
Form: Purified, in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Applications: Flow Cytometry (0.5-1ug/million cells in 0.1ml)
Immunofluorescence (0.5-1ug/ml)
Optimal dilution for a specific application should be determined.
Reactivity: HSB2 cells. Renal Cell, Ovarian carcinoma or Melanoma
Concentration: 0.2mg/ml
Storage: Can be stored at +4C. For long term storage, aliquot and store at -20C. Avoid repeated freezing and thawing cycles.
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