CD147 polyclonal, anti-human

Quantity: 100 µg

Background:
Emmprin, extracellular matrix metalloproteinase inducer, also known as Emmprin (BSG) or cluster of differentiation 147 (CD147) is a protein that in humans is encoded by the Emmprin gene. The human BSG gene is mapped to 19p13.3. This protein is a determinant for the Ok blood group system. BSG has been shown to be an essential receptor on red blood cells for the malaria parasite. It is a member of the immunoglobulin superfamily, with a structure related to the putative primordial form of the family. As members of the immunoglobulin superfamily, it plays fundamental roles in intercellular recognition involved in various immunologic phenomena, differentiation, and development. BSG is thought also to play a role in intercellular recognition. It also regulates several distinct functions, such as spermatogenesis, expression of the monocarboxylate transporter and the responsiveness of lymphocytes. BSG is a type I integral membrane receptor that has many ligands, including the cyclophilin (CyP) proteins Cyp-A and CyP-B and certain integrins. It is expressed by many cell types, including epithelial cells, endothelial cells and leukocytes.

Description:
Rabbit IgG polyclonal antibody for Basigin (BSG) detection. Tested with WB in Human.

Synonyms:
5A11 antigen antibody, 5F7 antibody, BASI_HUMAN antibody, Basigin (Ok blood group) antibody, Basigin antibody, Blood brain barrier HT7 antigen antibody, BSG antibody, CD 147 antibody, CD147 antibody, CD147 antigen antibody, Collagenase stimulatory factor antibody, Emmprin antibody, Extracellular matrix metalloproteinase inducer antibody, Leukocyte activation antigen M6 antibody, M 6 antibody, M6 antibody, M6 leukocyte activation antigen antibody, Neurothelin antibody, OK antibody, OK blood group antibody, OK blood group antigen antibody, TCSF antibody, Tumor cell derived collagenase stimulatory factor antibody, Tumor cell-derived collagenase stimulatory factor antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
E.coli-derived human CD147 recombinant protein (Position: E53-S385). Human CD147 shares 64% and 65% amino acid (aa) sequence identity with mouse and rat CD147, respectively.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.