CD148 (clone 1D2C11), anti-human
€0.00
In stock
SKU
BT-MCA4258
Catalog Number: BT-MCA4258
Size(s): 50μL, 100μL
Isotype: Mouse IgG2b
Reactivity: human
Application(s): FCM
Datasheet
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Size(s): 50μL, 100μL
Isotype: Mouse IgG2b
Reactivity: human
Application(s): FCM
Datasheet
Request Information
Background:
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes, including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region containing five fibronectin type III repeats, a single transmembrane region, and a single intracytoplasmic catalytic domain, and thus represents a receptor-type PTP. This protein is present in all hematopoietic lineages, and was shown to negatively regulate T cell receptor signaling possibly through interfering with the phosphorylation of Phospholipase C Gamma 1 and Linker for Activation of T Cells. This protein can also dephosphorylate the PDGF beta receptor, and may be involved in UV-induced signal transduction. Multiple transcript variants encoding different isoforms have been found for this gene.
Research Area: Others
Synonyms: PTPRJ, DEP1, SCC1, HPTPeta, R-PTP-ETA
Immunogen: Purified recombinant fragment of human CD148 (AA: extra 36-210) expressed in E. Coli.
Formulation: Purified antibody in PBS with 0.05% sodium azide
Storage:
4°C|-20°C for long term storage
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes, including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region containing five fibronectin type III repeats, a single transmembrane region, and a single intracytoplasmic catalytic domain, and thus represents a receptor-type PTP. This protein is present in all hematopoietic lineages, and was shown to negatively regulate T cell receptor signaling possibly through interfering with the phosphorylation of Phospholipase C Gamma 1 and Linker for Activation of T Cells. This protein can also dephosphorylate the PDGF beta receptor, and may be involved in UV-induced signal transduction. Multiple transcript variants encoding different isoforms have been found for this gene.
Research Area: Others
Synonyms: PTPRJ, DEP1, SCC1, HPTPeta, R-PTP-ETA
Immunogen: Purified recombinant fragment of human CD148 (AA: extra 36-210) expressed in E. Coli.
Formulation: Purified antibody in PBS with 0.05% sodium azide
Storage:
4°C|-20°C for long term storage
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