CD15 (clone HI98) FITC, anti-human
€435.00
In stock
SKU
251004
Protein Family: Cellular Antigens, Glycosyltransferases
Pathway and Disease: Glycan Biosynthesis and Metabolism, Immune System
Description:
The CD15 (HI98) antibody recognizes a 220 kDa carbohydrate antigen–Lacto–N–fucopentaose III, also called Lewis X, X-hapten, and SSEA-I. CD15 antigen is expressed on mature granulocytes (strongly), monocytes (weakly), immature bone marrow cells of myelomonocytic lineage, peripheral blood T lymphocytes (weakly), and some T-cells. CD15 antigen is also expressed on leukemia cells of myelomonocytic origin, Langerhans cells, a variety of carcinoma cells (preferentially adenocarcinomas), and occasionally on lymphocytic leukemia cells. CD15 is absent from B lymphocytes, erythrocytes and platelets. A soluble form of CD15 exists in serum (plasma) besides a membrane form. CD15 antigen plays a role in mediating phagocytosis, bactericidal activity and chemotaxis.
Alternate Names: Alpha-(1, 3)-fucosyltransferase, Galactoside 3-L-fucosyltransferase, Fucosyltransferase 4, FucT-IV, Fuc-TIV, ELAM-1 ligand fucosyltransferase, CD15, FUT4, ELFT, FCT3A
Application Notes: FC with whole blood: 100 μl blood + 20 μl antibody; FC with cells: 10E6 cells + 20 μl antibody. FC: 1:200-1:1,000
Accession No.: P22083, NP_002024
Format: Each vial contains 2 ml IgM (100 tests) in PBS pH7.4, 0.1% BSA with 0.09% sodium azide. Antibody was purified by hydroxyapatite chromatography.
Storage:
Store at 4°C. Product is guaranteed 6 months from the date of shipment.
Product Citations:
Shen DC. et al. 1989. J. Hematol, 10(7): 350
Guan Q. et al. 1993. Tissue Antigens. 42(4): 365.
Pathway and Disease: Glycan Biosynthesis and Metabolism, Immune System
Description:
The CD15 (HI98) antibody recognizes a 220 kDa carbohydrate antigen–Lacto–N–fucopentaose III, also called Lewis X, X-hapten, and SSEA-I. CD15 antigen is expressed on mature granulocytes (strongly), monocytes (weakly), immature bone marrow cells of myelomonocytic lineage, peripheral blood T lymphocytes (weakly), and some T-cells. CD15 antigen is also expressed on leukemia cells of myelomonocytic origin, Langerhans cells, a variety of carcinoma cells (preferentially adenocarcinomas), and occasionally on lymphocytic leukemia cells. CD15 is absent from B lymphocytes, erythrocytes and platelets. A soluble form of CD15 exists in serum (plasma) besides a membrane form. CD15 antigen plays a role in mediating phagocytosis, bactericidal activity and chemotaxis.
Alternate Names: Alpha-(1, 3)-fucosyltransferase, Galactoside 3-L-fucosyltransferase, Fucosyltransferase 4, FucT-IV, Fuc-TIV, ELAM-1 ligand fucosyltransferase, CD15, FUT4, ELFT, FCT3A
Application Notes: FC with whole blood: 100 μl blood + 20 μl antibody; FC with cells: 10E6 cells + 20 μl antibody. FC: 1:200-1:1,000
Accession No.: P22083, NP_002024
Format: Each vial contains 2 ml IgM (100 tests) in PBS pH7.4, 0.1% BSA with 0.09% sodium azide. Antibody was purified by hydroxyapatite chromatography.
Storage:
Store at 4°C. Product is guaranteed 6 months from the date of shipment.
Product Citations:
Shen DC. et al. 1989. J. Hematol, 10(7): 350
Guan Q. et al. 1993. Tissue Antigens. 42(4): 365.
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