CD156c (ADAM10) polyclonal, anti-human

Quantity: 100 µg

Background:
ADAM10, A Disintegrin and Metalloproteinase Domain 10, is also know as AD10. ADAM10 is a member of the ADAM family and members of this family are cell surface proteins with a unique structure possessing both potential adhesion and protease function. The ADAM10 gene is mapped to chromosome 15q21.3-q23. ADAM proteins contain an N-terminal signal sequence, followed by a prodomain, a metalloprotease-like domain, a disintegrin-like domain, a cysteine-rich region, an EGF -like repeat, a transmembrane domain, and a C-terminal cytoplasmic tail. Conversion of the membrane-bound precursor to a secreted mature protein is mediated by a protease termed TNFA convertase. ADAM10 possesses TNFA convertase activity.

Description:
Rabbit IgG polyclonal antibody for Disintegrin and metalloproteinase domain-containing protein 10 (ADAM10) detection. Tested with WB in Human.

Synonyms:
A disintegrin and metalloprotease domain 10 antibody, A disintegrin and metalloproteinase domain 10 antibody, AD 10 antibody, AD10 antibody, ADA10_HUMAN antibody, ADAM 10 antibody, ADAM metallopeptidase domain 10 antibody, ADAM10 antibody, CD 156c antibody, CD156c antibody, CD156c antigen antibody, CDw156 antibody, disintegrin and metalloproteinase domain containing protein 10 antibody, Disintegrin and metalloproteinase domain-containing protein 10 antibody, HsT 18717 antibody, HsT18717 antibody, Kuz antibody, Kuzbanian antibody, Kuzbanian protein homolog antibody, MADM antibody, Mammalian disintegrin metalloprotease antibody, Mammalian disintegrin-metalloprotease antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human ADAM10(612-627aa SVQWSRHFSGRTITLQ).

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.