CD159a/c Polyclonal Antibody

Background:
Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells.

Research Area: Cancer, Immunology

Synonyms:
C lectin type II protein, CD159 antigen like family member A, CD159 antigen-like family member A, CD159a, CD159a antigen, Killer cell lectin like receptor subfamily C member 1, KLRC1, MGC13374, MGC59791, Natural killer cell lectin, Natural killer cell protein group 2-A1, Natural killer cell receptor NKG2A, Natural killer group protein 2, NK cell receptor A, NKG2 1/B activating NK receptor, NKG2 A, NKG2 A/B activating NK receptor, NKG2 A/B type II integral membrane protein, NKG2 A/NKG2 B type II integral membrane protein, NKG2, NKG2 B, NKG2-1/B activating NK receptor, NKG2-A/B-activating NK receptor, NKG2-A/NKG2-B type II integral membrane protein, NKG2A, NKG2A, NKG2B, rNKG2A

Immunogen: Recombinant protein of human KLRC1

Swissprot: P26715
Gene Accession: BC053840

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.3 mg/mL
Dilution: IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-9616/sc-9619/sc-9620/sc-9617