CD16 (clone HI16a), anti-human
€362.00
In stock
SKU
250949
Catalog Nr.: 250949
Size: 0.1 mg
Isotype: mouse IgG1
Applications: E, FC, IHC
Datasheet
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Size: 0.1 mg
Isotype: mouse IgG1
Applications: E, FC, IHC
Datasheet
Request Information
Protein Family: Cellular Antigens
Pathway and Disease: Immune System
Description:
The CD16 (HI16a) antibody recognizes a 50-60 kDa transmembrane protein, a low affinity Fc receptor for IgG (FcRIII), which is a NK cell-associated antigen. CD16 antigen is expressed on the large majority of NK cells, granulocytes (eosinophils excepted), monocytes/macrophages and a subset of T cells. CD16 antigen is involved in signal transduction, NK cell activation and antibody-dependent cellular cytotoxicity (ADCC).
Alternate Names: Low affinity immunoglobulin gamma Fc region receptor III, IgG Fc receptor III, Fc-gamma RIII, FcRIII, FcRIII, FcR-10, CD16 antigen, FCGR3, CD16, FCG3, FCGR3, IGFR3
Application Notes: Purified antibody is suitable for immunohistochemistry with acetone-fixed frozen sections. E: 1:500-1:1,000; FC: 1:200-1:1,000; IHC: 1:200-1:500
Accession No.: P08637, O75015
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Product Citations:
Ambarus C et al. 2012. Research Article. Arthritis Research and Therapy. 14: R47. PMID# 22494514. like Knapp W. et al. eds. 1989. Leucocyte Typing IV: White Cell Differentiation Antigens. P798, 1078, Oxford University Press, New York
Barclay NA., et al. Eds 1993. The Leukocyte Antigen Facts Book, CD16 section, Academic Press Inc., San Diego, California, p 136.
Pathway and Disease: Immune System
Description:
The CD16 (HI16a) antibody recognizes a 50-60 kDa transmembrane protein, a low affinity Fc receptor for IgG (FcRIII), which is a NK cell-associated antigen. CD16 antigen is expressed on the large majority of NK cells, granulocytes (eosinophils excepted), monocytes/macrophages and a subset of T cells. CD16 antigen is involved in signal transduction, NK cell activation and antibody-dependent cellular cytotoxicity (ADCC).
Alternate Names: Low affinity immunoglobulin gamma Fc region receptor III, IgG Fc receptor III, Fc-gamma RIII, FcRIII, FcRIII, FcR-10, CD16 antigen, FCGR3, CD16, FCG3, FCGR3, IGFR3
Application Notes: Purified antibody is suitable for immunohistochemistry with acetone-fixed frozen sections. E: 1:500-1:1,000; FC: 1:200-1:1,000; IHC: 1:200-1:500
Accession No.: P08637, O75015
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Product Citations:
Ambarus C et al. 2012. Research Article. Arthritis Research and Therapy. 14: R47. PMID# 22494514. like Knapp W. et al. eds. 1989. Leucocyte Typing IV: White Cell Differentiation Antigens. P798, 1078, Oxford University Press, New York
Barclay NA., et al. Eds 1993. The Leukocyte Antigen Facts Book, CD16 section, Academic Press Inc., San Diego, California, p 136.
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