CD167a (DDR1) (clone 2G4E12), anti-human
€421.00
In stock
SKU
252798
Protein Family: Enzymes, Protein Kinases, Receptors and Channels
Pathway and Disease: Cell Communication
Description:
DDR1 (Epithelial discoidin domain-containing receptor 1, CD167a) is a receptor tyrosine kinase involved in cell-cell interactions and recognition. It is expressed in epithelial cells especially in the kidney, lung, gastrointestinal tract, and brain, and more highly in human breast, ovarian, esophageal, and pediatric brain tumors. Types I-VI collagen all induce the autophosphorylation of DDR1. Collagen regulates the interaction of DDR1 with KIBRA (WWC1), activating MAPK; these events are involved in mammary gland development.
Alternate Names: Epithelial discoidin domain-containing receptor 1, Epithelial discoidin domain receptor 1, Tyrosine kinase DDR, Discoidin receptor tyrosine kinase, Tyrosine-protein kinase CAK, Cell adhesion kinase, TRK E, Protein-tyrosine kinase RTK 6, CD167a antigen, HGK2, DDR1, EDDR1, NEP, NTRK4, PTK3A, RTK6, TRKE
Application Notes: WB: 1:500-1:2000
Accession No.: Q08345, NP_054699
Antigen: Purified recombinant fragment of DDR1(aa602-681) expressed in E. coli.
Format: Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
Storage:
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
Pathway and Disease: Cell Communication
Description:
DDR1 (Epithelial discoidin domain-containing receptor 1, CD167a) is a receptor tyrosine kinase involved in cell-cell interactions and recognition. It is expressed in epithelial cells especially in the kidney, lung, gastrointestinal tract, and brain, and more highly in human breast, ovarian, esophageal, and pediatric brain tumors. Types I-VI collagen all induce the autophosphorylation of DDR1. Collagen regulates the interaction of DDR1 with KIBRA (WWC1), activating MAPK; these events are involved in mammary gland development.
Alternate Names: Epithelial discoidin domain-containing receptor 1, Epithelial discoidin domain receptor 1, Tyrosine kinase DDR, Discoidin receptor tyrosine kinase, Tyrosine-protein kinase CAK, Cell adhesion kinase, TRK E, Protein-tyrosine kinase RTK 6, CD167a antigen, HGK2, DDR1, EDDR1, NEP, NTRK4, PTK3A, RTK6, TRKE
Application Notes: WB: 1:500-1:2000
Accession No.: Q08345, NP_054699
Antigen: Purified recombinant fragment of DDR1(aa602-681) expressed in E. coli.
Format: Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
Storage:
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
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