CD168 rabbit polyclonal, anti-human, mouse, rat

Backgroud: The protein encoded by this gene is involved in cell motility. It is expressed in breast tissue and together with other proteins, it forms a complex with BRCA1 and BRCA2, thus is potentially associated with higher risk of breast cancer. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Dec 2008],function:Involved in cell motility. When hyaluronan binds to HMMR, the phosphorylation of a number of proteins, including the focal adhesion kinase occurs. May also be involved in cellular transformation and metastasis formation, and in regulating extracellular-regulated kinase (ERK) activity.,subunit:Subunit of the HARC complex.,tissue specificity:Expressed in breast cancer cell lines and in normal breast tissue.,

Synonyms: Hyaluronan mediated motility receptor (Intracellular hyaluronic acid-binding protein, Receptor for hyaluronan-mediated motility, CD antigen CD168)

Gene Name: HMMR IHABP RHAMM

Gene ID: 3161

SwissProt ID: O75330

Purification: Affinity purification

Storage: Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.